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The requirement for mitochondrial respiration in cancer varies with disease stage

The roles for glycolytic and respiratory metabolism in supporting in vivo tumor growth in different contexts are not well understood. In this issue of PLOS Biology, a new study reveals that primary and metastatic tumors demonstrate divergent metabolic requirements.

Detalles Bibliográficos
Autores principales: Sheehan, Colin, Muir, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506606/
https://www.ncbi.nlm.nih.gov/pubmed/36149877
http://dx.doi.org/10.1371/journal.pbio.3001800
Descripción
Sumario:The roles for glycolytic and respiratory metabolism in supporting in vivo tumor growth in different contexts are not well understood. In this issue of PLOS Biology, a new study reveals that primary and metastatic tumors demonstrate divergent metabolic requirements.