Cargando…

A Unique Presentation of Extrapulmonary Legionella: Rhabdomyolysis-Induced Acute Renal Failure and Cerebellar Dysfunction

Legionella is most known for causing pneumonia. However, it is a systemic disease that can directly cause severe multi-organ injury in what is sometimes referred to as "extrapulmonary Legionella." In this case report, a reasonably healthy 80-year-old man is found to have Legionella pneumon...

Descripción completa

Detalles Bibliográficos
Autores principales: Olson, Erik, Murshad, Minhaz, Amin, Tasnuva, Udongwo, Ndausung, Chaughtai, Saira, Hossain, Mohammad A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506674/
https://www.ncbi.nlm.nih.gov/pubmed/36168373
http://dx.doi.org/10.7759/cureus.28396
_version_ 1784796781611057152
author Olson, Erik
Murshad, Minhaz
Amin, Tasnuva
Udongwo, Ndausung
Chaughtai, Saira
Hossain, Mohammad A
author_facet Olson, Erik
Murshad, Minhaz
Amin, Tasnuva
Udongwo, Ndausung
Chaughtai, Saira
Hossain, Mohammad A
author_sort Olson, Erik
collection PubMed
description Legionella is most known for causing pneumonia. However, it is a systemic disease that can directly cause severe multi-organ injury in what is sometimes referred to as "extrapulmonary Legionella." In this case report, a reasonably healthy 80-year-old man is found to have Legionella pneumonia complicated by rhabdomyolysis with acute, severe, non-oliguric acute kidney injury, uremic encephalopathy, transaminitis, and cerebellar dysfunction. With a 14-day course of azithromycin and prompt initiation of dialysis, the patient’s pneumonia and systemic sequelae improved. This case demonstrates the importance of considering Legionella in the differential diagnosis of patients who present with community-acquired pneumonia and multi-organ dysfunction. Prompt diagnosis and management may decrease mortality associated with this disease sequela.
format Online
Article
Text
id pubmed-9506674
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-95066742022-09-26 A Unique Presentation of Extrapulmonary Legionella: Rhabdomyolysis-Induced Acute Renal Failure and Cerebellar Dysfunction Olson, Erik Murshad, Minhaz Amin, Tasnuva Udongwo, Ndausung Chaughtai, Saira Hossain, Mohammad A Cureus Neurology Legionella is most known for causing pneumonia. However, it is a systemic disease that can directly cause severe multi-organ injury in what is sometimes referred to as "extrapulmonary Legionella." In this case report, a reasonably healthy 80-year-old man is found to have Legionella pneumonia complicated by rhabdomyolysis with acute, severe, non-oliguric acute kidney injury, uremic encephalopathy, transaminitis, and cerebellar dysfunction. With a 14-day course of azithromycin and prompt initiation of dialysis, the patient’s pneumonia and systemic sequelae improved. This case demonstrates the importance of considering Legionella in the differential diagnosis of patients who present with community-acquired pneumonia and multi-organ dysfunction. Prompt diagnosis and management may decrease mortality associated with this disease sequela. Cureus 2022-08-25 /pmc/articles/PMC9506674/ /pubmed/36168373 http://dx.doi.org/10.7759/cureus.28396 Text en Copyright © 2022, Olson et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurology
Olson, Erik
Murshad, Minhaz
Amin, Tasnuva
Udongwo, Ndausung
Chaughtai, Saira
Hossain, Mohammad A
A Unique Presentation of Extrapulmonary Legionella: Rhabdomyolysis-Induced Acute Renal Failure and Cerebellar Dysfunction
title A Unique Presentation of Extrapulmonary Legionella: Rhabdomyolysis-Induced Acute Renal Failure and Cerebellar Dysfunction
title_full A Unique Presentation of Extrapulmonary Legionella: Rhabdomyolysis-Induced Acute Renal Failure and Cerebellar Dysfunction
title_fullStr A Unique Presentation of Extrapulmonary Legionella: Rhabdomyolysis-Induced Acute Renal Failure and Cerebellar Dysfunction
title_full_unstemmed A Unique Presentation of Extrapulmonary Legionella: Rhabdomyolysis-Induced Acute Renal Failure and Cerebellar Dysfunction
title_short A Unique Presentation of Extrapulmonary Legionella: Rhabdomyolysis-Induced Acute Renal Failure and Cerebellar Dysfunction
title_sort unique presentation of extrapulmonary legionella: rhabdomyolysis-induced acute renal failure and cerebellar dysfunction
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506674/
https://www.ncbi.nlm.nih.gov/pubmed/36168373
http://dx.doi.org/10.7759/cureus.28396
work_keys_str_mv AT olsonerik auniquepresentationofextrapulmonarylegionellarhabdomyolysisinducedacuterenalfailureandcerebellardysfunction
AT murshadminhaz auniquepresentationofextrapulmonarylegionellarhabdomyolysisinducedacuterenalfailureandcerebellardysfunction
AT amintasnuva auniquepresentationofextrapulmonarylegionellarhabdomyolysisinducedacuterenalfailureandcerebellardysfunction
AT udongwondausung auniquepresentationofextrapulmonarylegionellarhabdomyolysisinducedacuterenalfailureandcerebellardysfunction
AT chaughtaisaira auniquepresentationofextrapulmonarylegionellarhabdomyolysisinducedacuterenalfailureandcerebellardysfunction
AT hossainmohammada auniquepresentationofextrapulmonarylegionellarhabdomyolysisinducedacuterenalfailureandcerebellardysfunction
AT olsonerik uniquepresentationofextrapulmonarylegionellarhabdomyolysisinducedacuterenalfailureandcerebellardysfunction
AT murshadminhaz uniquepresentationofextrapulmonarylegionellarhabdomyolysisinducedacuterenalfailureandcerebellardysfunction
AT amintasnuva uniquepresentationofextrapulmonarylegionellarhabdomyolysisinducedacuterenalfailureandcerebellardysfunction
AT udongwondausung uniquepresentationofextrapulmonarylegionellarhabdomyolysisinducedacuterenalfailureandcerebellardysfunction
AT chaughtaisaira uniquepresentationofextrapulmonarylegionellarhabdomyolysisinducedacuterenalfailureandcerebellardysfunction
AT hossainmohammada uniquepresentationofextrapulmonarylegionellarhabdomyolysisinducedacuterenalfailureandcerebellardysfunction