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A Unique Presentation of Extrapulmonary Legionella: Rhabdomyolysis-Induced Acute Renal Failure and Cerebellar Dysfunction
Legionella is most known for causing pneumonia. However, it is a systemic disease that can directly cause severe multi-organ injury in what is sometimes referred to as "extrapulmonary Legionella." In this case report, a reasonably healthy 80-year-old man is found to have Legionella pneumon...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506674/ https://www.ncbi.nlm.nih.gov/pubmed/36168373 http://dx.doi.org/10.7759/cureus.28396 |
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author | Olson, Erik Murshad, Minhaz Amin, Tasnuva Udongwo, Ndausung Chaughtai, Saira Hossain, Mohammad A |
author_facet | Olson, Erik Murshad, Minhaz Amin, Tasnuva Udongwo, Ndausung Chaughtai, Saira Hossain, Mohammad A |
author_sort | Olson, Erik |
collection | PubMed |
description | Legionella is most known for causing pneumonia. However, it is a systemic disease that can directly cause severe multi-organ injury in what is sometimes referred to as "extrapulmonary Legionella." In this case report, a reasonably healthy 80-year-old man is found to have Legionella pneumonia complicated by rhabdomyolysis with acute, severe, non-oliguric acute kidney injury, uremic encephalopathy, transaminitis, and cerebellar dysfunction. With a 14-day course of azithromycin and prompt initiation of dialysis, the patient’s pneumonia and systemic sequelae improved. This case demonstrates the importance of considering Legionella in the differential diagnosis of patients who present with community-acquired pneumonia and multi-organ dysfunction. Prompt diagnosis and management may decrease mortality associated with this disease sequela. |
format | Online Article Text |
id | pubmed-9506674 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-95066742022-09-26 A Unique Presentation of Extrapulmonary Legionella: Rhabdomyolysis-Induced Acute Renal Failure and Cerebellar Dysfunction Olson, Erik Murshad, Minhaz Amin, Tasnuva Udongwo, Ndausung Chaughtai, Saira Hossain, Mohammad A Cureus Neurology Legionella is most known for causing pneumonia. However, it is a systemic disease that can directly cause severe multi-organ injury in what is sometimes referred to as "extrapulmonary Legionella." In this case report, a reasonably healthy 80-year-old man is found to have Legionella pneumonia complicated by rhabdomyolysis with acute, severe, non-oliguric acute kidney injury, uremic encephalopathy, transaminitis, and cerebellar dysfunction. With a 14-day course of azithromycin and prompt initiation of dialysis, the patient’s pneumonia and systemic sequelae improved. This case demonstrates the importance of considering Legionella in the differential diagnosis of patients who present with community-acquired pneumonia and multi-organ dysfunction. Prompt diagnosis and management may decrease mortality associated with this disease sequela. Cureus 2022-08-25 /pmc/articles/PMC9506674/ /pubmed/36168373 http://dx.doi.org/10.7759/cureus.28396 Text en Copyright © 2022, Olson et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Neurology Olson, Erik Murshad, Minhaz Amin, Tasnuva Udongwo, Ndausung Chaughtai, Saira Hossain, Mohammad A A Unique Presentation of Extrapulmonary Legionella: Rhabdomyolysis-Induced Acute Renal Failure and Cerebellar Dysfunction |
title | A Unique Presentation of Extrapulmonary Legionella: Rhabdomyolysis-Induced Acute Renal Failure and Cerebellar Dysfunction |
title_full | A Unique Presentation of Extrapulmonary Legionella: Rhabdomyolysis-Induced Acute Renal Failure and Cerebellar Dysfunction |
title_fullStr | A Unique Presentation of Extrapulmonary Legionella: Rhabdomyolysis-Induced Acute Renal Failure and Cerebellar Dysfunction |
title_full_unstemmed | A Unique Presentation of Extrapulmonary Legionella: Rhabdomyolysis-Induced Acute Renal Failure and Cerebellar Dysfunction |
title_short | A Unique Presentation of Extrapulmonary Legionella: Rhabdomyolysis-Induced Acute Renal Failure and Cerebellar Dysfunction |
title_sort | unique presentation of extrapulmonary legionella: rhabdomyolysis-induced acute renal failure and cerebellar dysfunction |
topic | Neurology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506674/ https://www.ncbi.nlm.nih.gov/pubmed/36168373 http://dx.doi.org/10.7759/cureus.28396 |
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