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Islet primary cilia motility controls insulin secretion
Primary cilia are specialized cell-surface organelles that mediate sensory perception and, in contrast to motile cilia and flagella, are thought to lack motility function. Here, we show that primary cilia in human and mouse pancreatic islets exhibit movement that is required for glucose-dependent in...
Autores principales: | Cho, Jung Hoon, Li, Zipeng A., Zhu, Lifei, Muegge, Brian D., Roseman, Henry F., Lee, Eun Young, Utterback, Toby, Woodhams, Louis G., Bayly, Philip V., Hughes, Jing W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506710/ https://www.ncbi.nlm.nih.gov/pubmed/36149960 http://dx.doi.org/10.1126/sciadv.abq8486 |
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