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Islet primary cilia motility controls insulin secretion

Primary cilia are specialized cell-surface organelles that mediate sensory perception and, in contrast to motile cilia and flagella, are thought to lack motility function. Here, we show that primary cilia in human and mouse pancreatic islets exhibit movement that is required for glucose-dependent in...

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Detalles Bibliográficos
Autores principales: Cho, Jung Hoon, Li, Zipeng A., Zhu, Lifei, Muegge, Brian D., Roseman, Henry F., Lee, Eun Young, Utterback, Toby, Woodhams, Louis G., Bayly, Philip V., Hughes, Jing W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506710/
https://www.ncbi.nlm.nih.gov/pubmed/36149960
http://dx.doi.org/10.1126/sciadv.abq8486

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