Rhomboid-catalyzed intramembrane proteolysis requires hydrophobic matching with the surrounding lipid bilayer

Membrane thinning by rhomboid proteins has been proposed to reduce hydrophobic mismatch, providing a unique environment for important functions ranging from intramembrane proteolysis to retrotranslocation in protein degradation. We show by in vitro reconstitution and solid-state nuclear magnetic res...

Descripción completa

Detalles Bibliográficos
Autores principales: Engberg, Oskar, Ulbricht, David, Döbel, Viola, Siebert, Verena, Frie, Christian, Penk, Anja, Lemberg, Marius K., Huster, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506719/
https://www.ncbi.nlm.nih.gov/pubmed/36149963
http://dx.doi.org/10.1126/sciadv.abq8303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506719/
https://www.ncbi.nlm.nih.gov/pubmed/36149963
http://dx.doi.org/10.1126/sciadv.abq8303

Ejemplares similares