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Self-assembling peptide nanofiber HIV vaccine elicits robust vaccine-induced antibody functions and modulates Fc glycosylation

To develop vaccines for certain key global pathogens such as HIV, it is crucial to elicit both neutralizing and non-neutralizing Fc-mediated effector antibody functions. Clinical evidence indicates that non-neutralizing antibody functions including antibody-dependent cellular cytotoxicity (ADCC) and...

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Detalles Bibliográficos
Autores principales: Chen, Jui-Lin, Fries, Chelsea N., Berendam, Stella J., Rodgers, Nicole S., Roe, Emily F., Wu, Yaoying, Li, Shuk Hang, Jain, Rishabh, Watts, Brian, Eudailey, Joshua, Barfield, Richard, Chan, Cliburn, Moody, M. Anthony, Saunders, Kevin O., Pollara, Justin, Permar, Sallie R., Collier, Joel H., Fouda, Genevieve G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506727/
https://www.ncbi.nlm.nih.gov/pubmed/36149967
http://dx.doi.org/10.1126/sciadv.abq0273