Activation of Neuroinflammation via mTOR Pathway is Disparately Regulated by Differential Target Multiplexed and Traditional Low-Rate Spinal Cord Stimulation in a Neuropathic Pain Model

INTRODUCTION: Spinal cord stimulation (SCS) has been used for decades to treat neuropathic pain conditions with limited understanding of its mechanisms of action. The mTOR pathway is a well-known co-factor in chronic pain and has not been previously linked to SCS therapy. Proteomic and phosphorylati...

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Detalles Bibliográficos
Autores principales: Tilley, Dana M, Vallejo, Ricardo, Vetri, Francesco, Platt, David C, Cedeno, David L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507284/
https://www.ncbi.nlm.nih.gov/pubmed/36156899
http://dx.doi.org/10.2147/JPR.S378490

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