Combined Treatment of Tanshinone I and Epirubicin Revealed Enhanced Inhibition of Hepatocellular Carcinoma by Targeting PI3K/AKT/HIF-1α

BACKGROUND: Epirubicin (EADM) is a common chemotherapeutic agent in hepatocellular carcinoma (HCC). The accumulation of hypoxia-inducible factor-1α (HIF-1α) is an important cause of drug resistance to EADM in HCC. Tanshinone I (Tan I) is an agent with promising anti-cancer effects alone or with othe...

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Detalles Bibliográficos
Autores principales: Zhao, Jiali, Lin, En, Cai, Chaonong, Zhang, Manyao, Li, Decheng, Cai, Shanglin, Zeng, Guifang, Yin, Zeren, Wang, Bo, Li, Peiping, Hong, Xiaopeng, Chen, Jiafan, Zou, Baojia, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507289/
https://www.ncbi.nlm.nih.gov/pubmed/36158238
http://dx.doi.org/10.2147/DDDT.S360691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507289/
https://www.ncbi.nlm.nih.gov/pubmed/36158238
http://dx.doi.org/10.2147/DDDT.S360691

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