Cargando…
NFAT1 Orchestrates Spinal Microglial Transcription and Promotes Microglial Proliferation via c‐MYC Contributing to Nerve Injury‐Induced Neuropathic Pain
Peripheral nerve injury‐induced spinal microglial proliferation plays a pivotal role in neuropathic pain. So far, key intracellular druggable molecules involved in this process are not identified. The nuclear factor of activated T‐cells (NFAT1) is a master regulator of immune cell proliferation. Whe...
Autores principales: | Jiang, Bao‐Chun, Ding, Ting‐Yu, Guo, Chang‐Yun, Bai, Xue‐Hui, Cao, De‐Li, Wu, Xiao‐Bo, Sha, Wei‐Lin, Jiang, Ming, Wu, Long‐Jun, Gao, Yong‐Jing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507349/ https://www.ncbi.nlm.nih.gov/pubmed/35892263 http://dx.doi.org/10.1002/advs.202201300 |
Ejemplares similares
-
Neuronal and microglial mechanisms of neuropathic pain
por: Zhuo, Min, et al.
Publicado: (2011) -
P2Y6 Receptor-Mediated Spinal Microglial Activation in Neuropathic Pain
por: Bian, Jiang, et al.
Publicado: (2019) -
Following Nerve Injury Neuregulin-1 Drives Microglial Proliferation and Neuropathic Pain via the MEK/ERK Pathway
por: Calvo, Margarita, et al.
Publicado: (2011) -
TMEM16F Regulates Spinal Microglial Function in Neuropathic Pain States
por: Batti, Laura, et al.
Publicado: (2016) -
Effects of norepinephrine on microglial neuroinflammation and neuropathic pain
por: Zou, He‐Lin, et al.
Publicado: (2021)