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Comparative Study of Multimodal Therapy in Facial Palsy Patients

Introduction  In chronic facial palsy, synkinetic muscle overactivity and shortening causes muscle stiffness resulting in reduced movement and functional activity. This article studies the role of multimodal therapy in improving outcomes. Methods  Seventy-five facial palsy patients completed facial...

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Autores principales: Neville, Catriona, Gwynn, Tamsin, Young, Karen, Jordan, Elizabeth, Malhotra, Raman, Nduka, Charles, Kannan, Ruben Yap
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical Publishers, Inc. 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507561/
https://www.ncbi.nlm.nih.gov/pubmed/36159376
http://dx.doi.org/10.1055/s-0042-1756352
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author Neville, Catriona
Gwynn, Tamsin
Young, Karen
Jordan, Elizabeth
Malhotra, Raman
Nduka, Charles
Kannan, Ruben Yap
author_facet Neville, Catriona
Gwynn, Tamsin
Young, Karen
Jordan, Elizabeth
Malhotra, Raman
Nduka, Charles
Kannan, Ruben Yap
author_sort Neville, Catriona
collection PubMed
description Introduction  In chronic facial palsy, synkinetic muscle overactivity and shortening causes muscle stiffness resulting in reduced movement and functional activity. This article studies the role of multimodal therapy in improving outcomes. Methods  Seventy-five facial palsy patients completed facial rehabilitation before being successfully discharged by the facial therapy team. The cohort was divided into four subgroups depending on the time of initial attendance post-onset. The requirement for facial therapy, chemodenervation, or surgery was assessed with East Grinstead Grade of Stiffness (EGGS). Outcomes were measured using the Facial Grading Scale (FGS), Facial Disability Index, House-Brackmann scores, and the Facial Clinimetric Evaluation scale. Results  FGS composite scores significantly improved posttherapy (mean-standard deviation, 60.13 ± 23.24 vs. 79.9 ± 13.01; confidence interval, –24.51 to –14.66, p  < 0.0001). Analysis of FGS subsets showed that synkinesis also reduced significantly ( p  < 0.0001). Increasingly, late clinical presentations were associated with patients requiring longer durations of chemodenervation treatment ( p  < 0.01), more chemodenervation episodes ( p  < 0.01), increased doses of botulinum toxin ( p  < 0.001), and having higher EGGS score ( p  < 0.001). Conclusions  This study shows that multimodal facial rehabilitation in the management of facial palsy is effective, even in patients with chronically neglected synkinesis. In terms of the latency periods between facial palsy onset and treatment initiation, patients presenting later than 2 years were still responsive to multimodal treatment albeit to a lesser extent, which we postulate is due to increasing muscle contracture within their facial muscles.
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spelling pubmed-95075612022-09-24 Comparative Study of Multimodal Therapy in Facial Palsy Patients Neville, Catriona Gwynn, Tamsin Young, Karen Jordan, Elizabeth Malhotra, Raman Nduka, Charles Kannan, Ruben Yap Arch Plast Surg Introduction  In chronic facial palsy, synkinetic muscle overactivity and shortening causes muscle stiffness resulting in reduced movement and functional activity. This article studies the role of multimodal therapy in improving outcomes. Methods  Seventy-five facial palsy patients completed facial rehabilitation before being successfully discharged by the facial therapy team. The cohort was divided into four subgroups depending on the time of initial attendance post-onset. The requirement for facial therapy, chemodenervation, or surgery was assessed with East Grinstead Grade of Stiffness (EGGS). Outcomes were measured using the Facial Grading Scale (FGS), Facial Disability Index, House-Brackmann scores, and the Facial Clinimetric Evaluation scale. Results  FGS composite scores significantly improved posttherapy (mean-standard deviation, 60.13 ± 23.24 vs. 79.9 ± 13.01; confidence interval, –24.51 to –14.66, p  < 0.0001). Analysis of FGS subsets showed that synkinesis also reduced significantly ( p  < 0.0001). Increasingly, late clinical presentations were associated with patients requiring longer durations of chemodenervation treatment ( p  < 0.01), more chemodenervation episodes ( p  < 0.01), increased doses of botulinum toxin ( p  < 0.001), and having higher EGGS score ( p  < 0.001). Conclusions  This study shows that multimodal facial rehabilitation in the management of facial palsy is effective, even in patients with chronically neglected synkinesis. In terms of the latency periods between facial palsy onset and treatment initiation, patients presenting later than 2 years were still responsive to multimodal treatment albeit to a lesser extent, which we postulate is due to increasing muscle contracture within their facial muscles. Thieme Medical Publishers, Inc. 2022-09-23 /pmc/articles/PMC9507561/ /pubmed/36159376 http://dx.doi.org/10.1055/s-0042-1756352 Text en The Korean Society of Plastic and Reconstructive Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Neville, Catriona
Gwynn, Tamsin
Young, Karen
Jordan, Elizabeth
Malhotra, Raman
Nduka, Charles
Kannan, Ruben Yap
Comparative Study of Multimodal Therapy in Facial Palsy Patients
title Comparative Study of Multimodal Therapy in Facial Palsy Patients
title_full Comparative Study of Multimodal Therapy in Facial Palsy Patients
title_fullStr Comparative Study of Multimodal Therapy in Facial Palsy Patients
title_full_unstemmed Comparative Study of Multimodal Therapy in Facial Palsy Patients
title_short Comparative Study of Multimodal Therapy in Facial Palsy Patients
title_sort comparative study of multimodal therapy in facial palsy patients
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507561/
https://www.ncbi.nlm.nih.gov/pubmed/36159376
http://dx.doi.org/10.1055/s-0042-1756352
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