Cargando…
Analysis of the Predictive Effect of Lactic Acid Combined with Cardiac Troponin T and 5-Hydroxytryptophan on the Severity of Sepsis in ICU Patients and Its Correlation with Prognosis
In order to explore the effective markers of presepsis in the prediction of clinical disease and disease severity, the predictive effect of lactic acid (Lac) combined with cardiac troponin T (cTnT) and 5-hydroxytryptophan (5-HT) on the severity of sepsis in intensive care unit (ICU) patients and its...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507666/ https://www.ncbi.nlm.nih.gov/pubmed/36185579 http://dx.doi.org/10.1155/2022/6215282 |
_version_ | 1784796888094998528 |
---|---|
author | Jiang, Meini Wu, Weidong Wang, Xiuzhe Zhao, Caixia |
author_facet | Jiang, Meini Wu, Weidong Wang, Xiuzhe Zhao, Caixia |
author_sort | Jiang, Meini |
collection | PubMed |
description | In order to explore the effective markers of presepsis in the prediction of clinical disease and disease severity, the predictive effect of lactic acid (Lac) combined with cardiac troponin T (cTnT) and 5-hydroxytryptophan (5-HT) on the severity of sepsis in intensive care unit (ICU) patients and its correlation with prognosis is investigated. A total of 85 sepsis patients admitted to the ICU of our hospital from January 2020 to June 2021 are selected to establish the ICU sepsis group, and 72 health examination patients who received physical examination in our hospital during the same period are included in the healthy control group. The experimental results demonstrate that combined detection mode of serum Lac, cTnT, and 5-HT indicators has a high predictive value for the condition of patients with ICU sepsis and those indicators are closely correlated with the prognosis of patients. It suggests that the follow-up clinical monitoring of serum Lac, cTnT, and 5-HT indicators for patients with ICU sepsis can evaluate their condition and improve and optimize the clinical diagnosis and treatment plan effectively. |
format | Online Article Text |
id | pubmed-9507666 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-95076662022-09-29 Analysis of the Predictive Effect of Lactic Acid Combined with Cardiac Troponin T and 5-Hydroxytryptophan on the Severity of Sepsis in ICU Patients and Its Correlation with Prognosis Jiang, Meini Wu, Weidong Wang, Xiuzhe Zhao, Caixia Contrast Media Mol Imaging Research Article In order to explore the effective markers of presepsis in the prediction of clinical disease and disease severity, the predictive effect of lactic acid (Lac) combined with cardiac troponin T (cTnT) and 5-hydroxytryptophan (5-HT) on the severity of sepsis in intensive care unit (ICU) patients and its correlation with prognosis is investigated. A total of 85 sepsis patients admitted to the ICU of our hospital from January 2020 to June 2021 are selected to establish the ICU sepsis group, and 72 health examination patients who received physical examination in our hospital during the same period are included in the healthy control group. The experimental results demonstrate that combined detection mode of serum Lac, cTnT, and 5-HT indicators has a high predictive value for the condition of patients with ICU sepsis and those indicators are closely correlated with the prognosis of patients. It suggests that the follow-up clinical monitoring of serum Lac, cTnT, and 5-HT indicators for patients with ICU sepsis can evaluate their condition and improve and optimize the clinical diagnosis and treatment plan effectively. Hindawi 2022-09-16 /pmc/articles/PMC9507666/ /pubmed/36185579 http://dx.doi.org/10.1155/2022/6215282 Text en Copyright © 2022 Meini Jiang et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Jiang, Meini Wu, Weidong Wang, Xiuzhe Zhao, Caixia Analysis of the Predictive Effect of Lactic Acid Combined with Cardiac Troponin T and 5-Hydroxytryptophan on the Severity of Sepsis in ICU Patients and Its Correlation with Prognosis |
title | Analysis of the Predictive Effect of Lactic Acid Combined with Cardiac Troponin T and 5-Hydroxytryptophan on the Severity of Sepsis in ICU Patients and Its Correlation with Prognosis |
title_full | Analysis of the Predictive Effect of Lactic Acid Combined with Cardiac Troponin T and 5-Hydroxytryptophan on the Severity of Sepsis in ICU Patients and Its Correlation with Prognosis |
title_fullStr | Analysis of the Predictive Effect of Lactic Acid Combined with Cardiac Troponin T and 5-Hydroxytryptophan on the Severity of Sepsis in ICU Patients and Its Correlation with Prognosis |
title_full_unstemmed | Analysis of the Predictive Effect of Lactic Acid Combined with Cardiac Troponin T and 5-Hydroxytryptophan on the Severity of Sepsis in ICU Patients and Its Correlation with Prognosis |
title_short | Analysis of the Predictive Effect of Lactic Acid Combined with Cardiac Troponin T and 5-Hydroxytryptophan on the Severity of Sepsis in ICU Patients and Its Correlation with Prognosis |
title_sort | analysis of the predictive effect of lactic acid combined with cardiac troponin t and 5-hydroxytryptophan on the severity of sepsis in icu patients and its correlation with prognosis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507666/ https://www.ncbi.nlm.nih.gov/pubmed/36185579 http://dx.doi.org/10.1155/2022/6215282 |
work_keys_str_mv | AT jiangmeini analysisofthepredictiveeffectoflacticacidcombinedwithcardiactroponintand5hydroxytryptophanontheseverityofsepsisinicupatientsanditscorrelationwithprognosis AT wuweidong analysisofthepredictiveeffectoflacticacidcombinedwithcardiactroponintand5hydroxytryptophanontheseverityofsepsisinicupatientsanditscorrelationwithprognosis AT wangxiuzhe analysisofthepredictiveeffectoflacticacidcombinedwithcardiactroponintand5hydroxytryptophanontheseverityofsepsisinicupatientsanditscorrelationwithprognosis AT zhaocaixia analysisofthepredictiveeffectoflacticacidcombinedwithcardiactroponintand5hydroxytryptophanontheseverityofsepsisinicupatientsanditscorrelationwithprognosis |