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Role of Bioinformatics Analysis in Early Differential Diagnosis of Ovarian Cancer
In order to solve the problem of early differential diagnosis of ovarian cancer, this paper proposes the role of bioinformatics analysis in early differential diagnosis of ovarian cancer. This method uses bioinformatics methods to mine the existing data in the tumor database and obtain tumor-related...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507672/ https://www.ncbi.nlm.nih.gov/pubmed/36185577 http://dx.doi.org/10.1155/2022/6129817 |
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author | Zhang, Lihua Zhao, Yuanyuan Li, Li Xin, Huadong |
author_facet | Zhang, Lihua Zhao, Yuanyuan Li, Li Xin, Huadong |
author_sort | Zhang, Lihua |
collection | PubMed |
description | In order to solve the problem of early differential diagnosis of ovarian cancer, this paper proposes the role of bioinformatics analysis in early differential diagnosis of ovarian cancer. This method uses bioinformatics methods to mine the existing data in the tumor database and obtain tumor-related molecules. It is an efficient method to obtain effective biomarkers, screen signal pathway molecules, and reveal the internal mechanism of tumor occurrence and development. Using this method can greatly improve the efficiency and reliability of screening diagnosis, prognosis, and treatment targets. The results showed that 5821 new lncRNA transcripts and 4611 new lncRNA genes were identified by lncScore from the assembled transcripts. 10 new lncRNA transcripts and 174 new lncRNA genes were found to be differentially expressed in ovarian cancer. |
format | Online Article Text |
id | pubmed-9507672 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-95076722022-09-29 Role of Bioinformatics Analysis in Early Differential Diagnosis of Ovarian Cancer Zhang, Lihua Zhao, Yuanyuan Li, Li Xin, Huadong Contrast Media Mol Imaging Research Article In order to solve the problem of early differential diagnosis of ovarian cancer, this paper proposes the role of bioinformatics analysis in early differential diagnosis of ovarian cancer. This method uses bioinformatics methods to mine the existing data in the tumor database and obtain tumor-related molecules. It is an efficient method to obtain effective biomarkers, screen signal pathway molecules, and reveal the internal mechanism of tumor occurrence and development. Using this method can greatly improve the efficiency and reliability of screening diagnosis, prognosis, and treatment targets. The results showed that 5821 new lncRNA transcripts and 4611 new lncRNA genes were identified by lncScore from the assembled transcripts. 10 new lncRNA transcripts and 174 new lncRNA genes were found to be differentially expressed in ovarian cancer. Hindawi 2022-09-16 /pmc/articles/PMC9507672/ /pubmed/36185577 http://dx.doi.org/10.1155/2022/6129817 Text en Copyright © 2022 Lihua Zhang et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Zhang, Lihua Zhao, Yuanyuan Li, Li Xin, Huadong Role of Bioinformatics Analysis in Early Differential Diagnosis of Ovarian Cancer |
title | Role of Bioinformatics Analysis in Early Differential Diagnosis of Ovarian Cancer |
title_full | Role of Bioinformatics Analysis in Early Differential Diagnosis of Ovarian Cancer |
title_fullStr | Role of Bioinformatics Analysis in Early Differential Diagnosis of Ovarian Cancer |
title_full_unstemmed | Role of Bioinformatics Analysis in Early Differential Diagnosis of Ovarian Cancer |
title_short | Role of Bioinformatics Analysis in Early Differential Diagnosis of Ovarian Cancer |
title_sort | role of bioinformatics analysis in early differential diagnosis of ovarian cancer |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507672/ https://www.ncbi.nlm.nih.gov/pubmed/36185577 http://dx.doi.org/10.1155/2022/6129817 |
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