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Evaluation of Lymphocyte-to-Monocyte Ratio and Mean Platelet Volume-to-Platelet Ratio in Rhegmatogenous Retinal Detachment

PURPOSE: To assess the predictive value of inflammatory blood biomarkers in rhegmatogenous retinal detachment (RRD) patients and its correlation with proliferative retinopathy (PVR) grade. METHODS: 82 RRD patients and 1 : 1 age- and gender-randomly matched cataract patients as the control group were...

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Autores principales: Xiao, Xuan, Song, Jiayi, Ye, Lin, Zuo, Wen, Yang, Hongxia, Chen, Changzheng, Zheng, Hongmei, Chen, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507743/
https://www.ncbi.nlm.nih.gov/pubmed/36157678
http://dx.doi.org/10.1155/2022/9127745
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author Xiao, Xuan
Song, Jiayi
Ye, Lin
Zuo, Wen
Yang, Hongxia
Chen, Changzheng
Zheng, Hongmei
Chen, Ting
author_facet Xiao, Xuan
Song, Jiayi
Ye, Lin
Zuo, Wen
Yang, Hongxia
Chen, Changzheng
Zheng, Hongmei
Chen, Ting
author_sort Xiao, Xuan
collection PubMed
description PURPOSE: To assess the predictive value of inflammatory blood biomarkers in rhegmatogenous retinal detachment (RRD) patients and its correlation with proliferative retinopathy (PVR) grade. METHODS: 82 RRD patients and 1 : 1 age- and gender-randomly matched cataract patients as the control group were included. The clinical features and laboratory parameters of all participants were collected and recorded, and the comprehensive index of inflammatory blood and its correlation with PVR were calculated. RESULTS: Monocytes and monocyte-to-high-density lipoprotein ratio (MHR) were significantly lower (P=0.005, P=0.044), while mean platelet volume (MPV), lymphocyte-to-monocyte ratio (LMR), and MPV-to-platelet ratio (MPR) were significantly higher in RRD patients as compared with the control group (P=0.013, P=0.019, P=0.037). LMR and MPR might be the predictors of RRD. The receiver operating characteristics analysis showed that the values of MPV, LMR, and MPR in RRD patients were 0.612, 0.606, and 0.594, respectively. PVR grade was not associated with inflammatory blood biomarkers. CONCLUSION: The increase in MPV, LMR, and MPR were associated with increased odds of RRD. LMR and MPR may be useful as inexpensive and effortless biomarkers for assessing the occurrence of RRD.
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spelling pubmed-95077432022-09-24 Evaluation of Lymphocyte-to-Monocyte Ratio and Mean Platelet Volume-to-Platelet Ratio in Rhegmatogenous Retinal Detachment Xiao, Xuan Song, Jiayi Ye, Lin Zuo, Wen Yang, Hongxia Chen, Changzheng Zheng, Hongmei Chen, Ting J Ophthalmol Research Article PURPOSE: To assess the predictive value of inflammatory blood biomarkers in rhegmatogenous retinal detachment (RRD) patients and its correlation with proliferative retinopathy (PVR) grade. METHODS: 82 RRD patients and 1 : 1 age- and gender-randomly matched cataract patients as the control group were included. The clinical features and laboratory parameters of all participants were collected and recorded, and the comprehensive index of inflammatory blood and its correlation with PVR were calculated. RESULTS: Monocytes and monocyte-to-high-density lipoprotein ratio (MHR) were significantly lower (P=0.005, P=0.044), while mean platelet volume (MPV), lymphocyte-to-monocyte ratio (LMR), and MPV-to-platelet ratio (MPR) were significantly higher in RRD patients as compared with the control group (P=0.013, P=0.019, P=0.037). LMR and MPR might be the predictors of RRD. The receiver operating characteristics analysis showed that the values of MPV, LMR, and MPR in RRD patients were 0.612, 0.606, and 0.594, respectively. PVR grade was not associated with inflammatory blood biomarkers. CONCLUSION: The increase in MPV, LMR, and MPR were associated with increased odds of RRD. LMR and MPR may be useful as inexpensive and effortless biomarkers for assessing the occurrence of RRD. Hindawi 2022-09-16 /pmc/articles/PMC9507743/ /pubmed/36157678 http://dx.doi.org/10.1155/2022/9127745 Text en Copyright © 2022 Xuan Xiao et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Xiao, Xuan
Song, Jiayi
Ye, Lin
Zuo, Wen
Yang, Hongxia
Chen, Changzheng
Zheng, Hongmei
Chen, Ting
Evaluation of Lymphocyte-to-Monocyte Ratio and Mean Platelet Volume-to-Platelet Ratio in Rhegmatogenous Retinal Detachment
title Evaluation of Lymphocyte-to-Monocyte Ratio and Mean Platelet Volume-to-Platelet Ratio in Rhegmatogenous Retinal Detachment
title_full Evaluation of Lymphocyte-to-Monocyte Ratio and Mean Platelet Volume-to-Platelet Ratio in Rhegmatogenous Retinal Detachment
title_fullStr Evaluation of Lymphocyte-to-Monocyte Ratio and Mean Platelet Volume-to-Platelet Ratio in Rhegmatogenous Retinal Detachment
title_full_unstemmed Evaluation of Lymphocyte-to-Monocyte Ratio and Mean Platelet Volume-to-Platelet Ratio in Rhegmatogenous Retinal Detachment
title_short Evaluation of Lymphocyte-to-Monocyte Ratio and Mean Platelet Volume-to-Platelet Ratio in Rhegmatogenous Retinal Detachment
title_sort evaluation of lymphocyte-to-monocyte ratio and mean platelet volume-to-platelet ratio in rhegmatogenous retinal detachment
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507743/
https://www.ncbi.nlm.nih.gov/pubmed/36157678
http://dx.doi.org/10.1155/2022/9127745
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