Bioactivities and Mechanism of Actions of Dendrobium officinale: A Comprehensive Review

Dendrobium officinale has a long history of being consumed as a functional food and medicinal herb for preventing and managing diseases. The phytochemical studies revealed that Dendrobium officinale contained abundant bioactive compounds, such as bibenzyls, polysaccharides, flavonoids, and alkaloids...

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Detalles Bibliográficos
Autores principales: Xu, Xiaoyu, Zhang, Cheng, Wang, Ning, Xu, Yu, Tang, Guoyi, Xu, Lin, Feng, Yibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507758/
https://www.ncbi.nlm.nih.gov/pubmed/36160715
http://dx.doi.org/10.1155/2022/6293355
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author Xu, Xiaoyu
Zhang, Cheng
Wang, Ning
Xu, Yu
Tang, Guoyi
Xu, Lin
Feng, Yibin
author_facet Xu, Xiaoyu
Zhang, Cheng
Wang, Ning
Xu, Yu
Tang, Guoyi
Xu, Lin
Feng, Yibin
author_sort Xu, Xiaoyu
collection PubMed
description Dendrobium officinale has a long history of being consumed as a functional food and medicinal herb for preventing and managing diseases. The phytochemical studies revealed that Dendrobium officinale contained abundant bioactive compounds, such as bibenzyls, polysaccharides, flavonoids, and alkaloids. The experimental studies showed that Dendrobium officinale and its bioactive compounds exerted multiple biological properties like antioxidant, anti-inflammatory, and immune-regulatory activities and showed various health benefits like anticancer, antidiabetes, cardiovascular protective, gastrointestinal modulatory, hepatoprotective, lung protective, and neuroprotective effects. In this review, we summarize the phytochemical studies, bioactivities, and the mechanism of actions of Dendrobium officinale, and the safety and current challenges are also discussed, which might provide new perspectives for its development of drug and functional food as well as clinical applications.
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spelling pubmed-95077582022-09-24 Bioactivities and Mechanism of Actions of Dendrobium officinale: A Comprehensive Review Xu, Xiaoyu Zhang, Cheng Wang, Ning Xu, Yu Tang, Guoyi Xu, Lin Feng, Yibin Oxid Med Cell Longev Review Article Dendrobium officinale has a long history of being consumed as a functional food and medicinal herb for preventing and managing diseases. The phytochemical studies revealed that Dendrobium officinale contained abundant bioactive compounds, such as bibenzyls, polysaccharides, flavonoids, and alkaloids. The experimental studies showed that Dendrobium officinale and its bioactive compounds exerted multiple biological properties like antioxidant, anti-inflammatory, and immune-regulatory activities and showed various health benefits like anticancer, antidiabetes, cardiovascular protective, gastrointestinal modulatory, hepatoprotective, lung protective, and neuroprotective effects. In this review, we summarize the phytochemical studies, bioactivities, and the mechanism of actions of Dendrobium officinale, and the safety and current challenges are also discussed, which might provide new perspectives for its development of drug and functional food as well as clinical applications. Hindawi 2022-09-16 /pmc/articles/PMC9507758/ /pubmed/36160715 http://dx.doi.org/10.1155/2022/6293355 Text en Copyright © 2022 Xiaoyu Xu et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Xu, Xiaoyu
Zhang, Cheng
Wang, Ning
Xu, Yu
Tang, Guoyi
Xu, Lin
Feng, Yibin
Bioactivities and Mechanism of Actions of Dendrobium officinale: A Comprehensive Review
title Bioactivities and Mechanism of Actions of Dendrobium officinale: A Comprehensive Review
title_full Bioactivities and Mechanism of Actions of Dendrobium officinale: A Comprehensive Review
title_fullStr Bioactivities and Mechanism of Actions of Dendrobium officinale: A Comprehensive Review
title_full_unstemmed Bioactivities and Mechanism of Actions of Dendrobium officinale: A Comprehensive Review
title_short Bioactivities and Mechanism of Actions of Dendrobium officinale: A Comprehensive Review
title_sort bioactivities and mechanism of actions of dendrobium officinale: a comprehensive review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507758/
https://www.ncbi.nlm.nih.gov/pubmed/36160715
http://dx.doi.org/10.1155/2022/6293355
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