Combinatorial treatment with statins and niclosamide prevents CRC dissemination by unhinging the MACC1-β-catenin-S100A4 axis of metastasis

Colorectal cancer (CRC) is the second-most common malignant disease worldwide, and metastasis is the main culprit of CRC-related death. Metachronous metastases remain to be an unpredictable, unpreventable, and fatal complication, and tracing the molecular chain of events that lead to metastasis woul...

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Detalles Bibliográficos
Autores principales: Kortüm, Benedikt, Radhakrishnan, Harikrishnan, Zincke, Fabian, Sachse, Christoph, Burock, Susen, Keilholz, Ulrich, Dahlmann, Mathias, Walther, Wolfgang, Dittmar, Gunnar, Kobelt, Dennis, Stein, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507965/
https://www.ncbi.nlm.nih.gov/pubmed/36008464
http://dx.doi.org/10.1038/s41388-022-02407-6

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