The inner nuclear membrane protein Lem2 coordinates RNA degradation at the nuclear periphery

Transcriptionally silent chromatin often localizes to the nuclear periphery. However, whether the nuclear envelope (NE) is a site for post-transcriptional gene repression is not well understood. Here we demonstrate that Schizosaccharomyces pombe Lem2, an NE protein, regulates nuclear-exosome-mediate...

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Detalles Bibliográficos
Autores principales: Martín Caballero, Lucía, Capella, Matías, Barrales, Ramón Ramos, Dobrev, Nikolay, van Emden, Thomas, Hirano, Yasuhiro, Suma Sreechakram, Vishnu N., Fischer-Burkart, Sabine, Kinugasa, Yasuha, Nevers, Alicia, Rougemaille, Mathieu, Sinning, Irmgard, Fischer, Tamás, Hiraoka, Yasushi, Braun, Sigurd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507967/
https://www.ncbi.nlm.nih.gov/pubmed/36123402
http://dx.doi.org/10.1038/s41594-022-00831-6

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