Cargando…
A high-throughput drug screen reveals means to differentiate triple-negative breast cancer
Plasticity delineates cancer subtypes with more or less favourable outcomes. In breast cancer, the subtype triple-negative lacks expression of major differentiation markers, e.g., estrogen receptor α (ERα), and its high cellular plasticity results in greater aggressiveness and poorer prognosis than...
Autores principales: | Vulin, Milica, Jehanno, Charly, Sethi, Atul, Correia, Ana Luísa, Obradović, Milan M. S., Couto, Joana Pinto, Coissieux, Marie-May, Diepenbruck, Maren, Preca, Bogdan-Tiberius, Volkmann, Katrin, der Maur, Priska Auf, Schmidt, Alexander, Münst, Simone, Sauteur, Loïc, Kloc, Michal, Palafox, Marta, Britschgi, Adrian, Unterreiner, Vincent, Galuba, Olaf, Claerr, Isabelle, Lopez-Romero, Sandra, Galli, Giorgio G., Baeschlin, Daniel, Okamoto, Ryoko, Soysal, Savas D., Mechera, Robert, Weber, Walter P., Radimerski, Thomas, Bentires-Alj, Mohamed |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507968/ https://www.ncbi.nlm.nih.gov/pubmed/36008466 http://dx.doi.org/10.1038/s41388-022-02429-0 |
Ejemplares similares
-
The NFIB‐ERO1A axis promotes breast cancer metastatic colonization of disseminated tumour cells
por: Zilli, Federica, et al.
Publicado: (2021) -
Feed‐forward loops between metastatic cancer cells and their microenvironment—the stage of escalation
por: Baumann, Zora, et al.
Publicado: (2022) -
PI3K inhibition circumvents resistance to SHP2 blockade in metastatic triple-negative breast cancer
por: Amante, Romain J., et al.
Publicado: (2023) -
N-acetylcysteine overcomes NF1 loss-driven resistance to PI3Kα inhibition in breast cancer
por: Auf der Maur, Priska, et al.
Publicado: (2023) -
Protein Tyrosine Phosphatase SHP2 Controls Interleukin-8 Expression in Breast Cancer Cells
por: Amante, Romain J., et al.
Publicado: (2022)