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Males and females with first episode psychosis present distinct profiles of social cognition and metacognition

Deficits in social cognition and metacognition impact the course of psychosis. Sex differences in social cognition and metacognition could explain heterogeneity in psychosis. 174 (58 females) patients with first-episode psychosis completed a clinical, neuropsychological, social cognitive, and metaco...

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Autores principales: Ferrer-Quintero, M., Fernández, D., López-Carrilero, R., Birulés, I., Barajas, A., Lorente-Rovira, E., Luengo, A., Díaz-Cutraro, L., Verdaguer, M., García-Mieres, H., Gutiérrez-Zotes, A., Grasa, E., Pousa, E., Huerta-Ramos, E., Pélaez, T., Barrigón, M. L., Gómez-Benito, J., González-Higueras, F., Ruiz-Delgado, I., Cid, J., Moritz, S., Sevilla-Llewellyn-Jones, J., Ochoa, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508015/
https://www.ncbi.nlm.nih.gov/pubmed/35802165
http://dx.doi.org/10.1007/s00406-022-01438-0
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author Ferrer-Quintero, M.
Fernández, D.
López-Carrilero, R.
Birulés, I.
Barajas, A.
Lorente-Rovira, E.
Luengo, A.
Díaz-Cutraro, L.
Verdaguer, M.
García-Mieres, H.
Gutiérrez-Zotes, A.
Grasa, E.
Pousa, E.
Huerta-Ramos, E.
Pélaez, T.
Barrigón, M. L.
Gómez-Benito, J.
González-Higueras, F.
Ruiz-Delgado, I.
Cid, J.
Moritz, S.
Sevilla-Llewellyn-Jones, J.
Ochoa, S.
author_facet Ferrer-Quintero, M.
Fernández, D.
López-Carrilero, R.
Birulés, I.
Barajas, A.
Lorente-Rovira, E.
Luengo, A.
Díaz-Cutraro, L.
Verdaguer, M.
García-Mieres, H.
Gutiérrez-Zotes, A.
Grasa, E.
Pousa, E.
Huerta-Ramos, E.
Pélaez, T.
Barrigón, M. L.
Gómez-Benito, J.
González-Higueras, F.
Ruiz-Delgado, I.
Cid, J.
Moritz, S.
Sevilla-Llewellyn-Jones, J.
Ochoa, S.
author_sort Ferrer-Quintero, M.
collection PubMed
description Deficits in social cognition and metacognition impact the course of psychosis. Sex differences in social cognition and metacognition could explain heterogeneity in psychosis. 174 (58 females) patients with first-episode psychosis completed a clinical, neuropsychological, social cognitive, and metacognitive assessment. Subsequent latent profile analysis split by sex yielded two clusters common to both sexes (a Homogeneous group, 53% and 79.3%, and an Indecisive group, 18.3% and 8.6% of males and females, respectively), a specific male profile characterized by presenting jumping to conclusions (28.7%) and a specific female profile characterized by cognitive biases (12.1%). Males and females in the homogeneous profile seem to have a more benign course of illness. Males with jumping to conclusions had more clinical symptoms and more neuropsychological deficits. Females with cognitive biases were younger and had lower self-esteem. These results suggest that males and females may benefit from specific targeted treatment and highlights the need to consider sex when planning interventions. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00406-022-01438-0.
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spelling pubmed-95080152022-09-25 Males and females with first episode psychosis present distinct profiles of social cognition and metacognition Ferrer-Quintero, M. Fernández, D. López-Carrilero, R. Birulés, I. Barajas, A. Lorente-Rovira, E. Luengo, A. Díaz-Cutraro, L. Verdaguer, M. García-Mieres, H. Gutiérrez-Zotes, A. Grasa, E. Pousa, E. Huerta-Ramos, E. Pélaez, T. Barrigón, M. L. Gómez-Benito, J. González-Higueras, F. Ruiz-Delgado, I. Cid, J. Moritz, S. Sevilla-Llewellyn-Jones, J. Ochoa, S. Eur Arch Psychiatry Clin Neurosci Original Paper Deficits in social cognition and metacognition impact the course of psychosis. Sex differences in social cognition and metacognition could explain heterogeneity in psychosis. 174 (58 females) patients with first-episode psychosis completed a clinical, neuropsychological, social cognitive, and metacognitive assessment. Subsequent latent profile analysis split by sex yielded two clusters common to both sexes (a Homogeneous group, 53% and 79.3%, and an Indecisive group, 18.3% and 8.6% of males and females, respectively), a specific male profile characterized by presenting jumping to conclusions (28.7%) and a specific female profile characterized by cognitive biases (12.1%). Males and females in the homogeneous profile seem to have a more benign course of illness. Males with jumping to conclusions had more clinical symptoms and more neuropsychological deficits. Females with cognitive biases were younger and had lower self-esteem. These results suggest that males and females may benefit from specific targeted treatment and highlights the need to consider sex when planning interventions. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00406-022-01438-0. Springer Berlin Heidelberg 2022-07-08 2022 /pmc/articles/PMC9508015/ /pubmed/35802165 http://dx.doi.org/10.1007/s00406-022-01438-0 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Paper
Ferrer-Quintero, M.
Fernández, D.
López-Carrilero, R.
Birulés, I.
Barajas, A.
Lorente-Rovira, E.
Luengo, A.
Díaz-Cutraro, L.
Verdaguer, M.
García-Mieres, H.
Gutiérrez-Zotes, A.
Grasa, E.
Pousa, E.
Huerta-Ramos, E.
Pélaez, T.
Barrigón, M. L.
Gómez-Benito, J.
González-Higueras, F.
Ruiz-Delgado, I.
Cid, J.
Moritz, S.
Sevilla-Llewellyn-Jones, J.
Ochoa, S.
Males and females with first episode psychosis present distinct profiles of social cognition and metacognition
title Males and females with first episode psychosis present distinct profiles of social cognition and metacognition
title_full Males and females with first episode psychosis present distinct profiles of social cognition and metacognition
title_fullStr Males and females with first episode psychosis present distinct profiles of social cognition and metacognition
title_full_unstemmed Males and females with first episode psychosis present distinct profiles of social cognition and metacognition
title_short Males and females with first episode psychosis present distinct profiles of social cognition and metacognition
title_sort males and females with first episode psychosis present distinct profiles of social cognition and metacognition
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508015/
https://www.ncbi.nlm.nih.gov/pubmed/35802165
http://dx.doi.org/10.1007/s00406-022-01438-0
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