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HSV-1 0∆NLS vaccine elicits a robust B lymphocyte response and preserves vision without HSV-1 glycoprotein M or thymidine kinase recognition

Effective experimental prophylactic vaccines against viral pathogens such as herpes simplex virus type 1 (HSV-1) have been shown to protect the host through T and/or B lymphocyte-driven responses. Previously, we found a live-attenuated HSV-1 mutant, 0ΔNLS used as a prophylactic vaccine, provided sig...

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Detalles Bibliográficos
Autores principales:	Gmyrek, Grzegorz B., Berube, Amanda N., Sjoelund, Virginie H., Carr, Daniel J. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508094/ https://www.ncbi.nlm.nih.gov/pubmed/36151255 http://dx.doi.org/10.1038/s41598-022-20180-0

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