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Influenza A virus use of BinCARD1 to facilitate the binding of viral NP to importin α7 is counteracted by TBK1-p62 axis-mediated autophagy

As a major component of the viral ribonucleoprotein (vRNP) complex in influenza A virus (IAV), nucleoprotein (NP) interacts with isoforms of importin α family members, leading to the import of itself  and vRNP complex into the nucleus, a process pivotal in the replication cycle of IAV. In this study...

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Detalles Bibliográficos
Autores principales: Wang, Xuyuan, Jiang, Li, Wang, Guangwen, Shi, Wenjun, Hu, Yuzhen, Wang, Bo, Zeng, Xianying, Tian, Guobin, Deng, Guohua, Shi, Jianzhong, Liu, Liling, Li, Chengjun, Chen, Hualan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508095/
https://www.ncbi.nlm.nih.gov/pubmed/36056146
http://dx.doi.org/10.1038/s41423-022-00906-w