Glial cell derived neurotrophic factor prevents western diet and palmitate-induced hepatocyte oxidative damage and death through SIRT3

Nonalcoholic fatty liver disease (NAFLD) is associated with increased oxidative stress that leads to hepatocyte and mitochondrial damage. In this study we investigated the mechanisms involved in the induction of oxidative stress and impairment of mitochondrial quality control and mitophagy in hepato...

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Detalles Bibliográficos
Autores principales: Mwangi, Simon Musyoka, Li, Ge, Balasubramaniam, Arun, Merlin, Didier, Dawson, Paul A., Jang, Young C., Hart, C. Michael, Czaja, Mark J., Srinivasan, Shanthi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508117/
https://www.ncbi.nlm.nih.gov/pubmed/36151131
http://dx.doi.org/10.1038/s41598-022-20101-1

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