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A distinct symptom pattern emerges for COVID-19 long-haul: a nationwide study

Long-haul COVID-19, also called post-acute sequelae of SARS-CoV-2 (PASC), is a new illness caused by SARS-CoV-2 infection and characterized by the persistence of symptoms. The purpose of this cross-sectional study was to identify a distinct and significant temporal pattern of PASC symptoms (symptom...

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Detalles Bibliográficos
Autores principales: Pinto, Melissa D., Downs, Charles A., Huang, Yong, El-Azab, Sarah A., Ramrakhiani, Nathan S., Barisano, Anthony, Yu, Lu, Taylor, Kaitlyn, Esperanca, Alvaro, Abrahim, Heather L., Hughes, Thomas, Herrera, Maria Giraldo, Rahamani, Amir M., Dutt, Nikil, Chakraborty, Rana, Mendiola, Christian, Lambert, Natalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508141/
https://www.ncbi.nlm.nih.gov/pubmed/36151129
http://dx.doi.org/10.1038/s41598-022-20214-7
Descripción
Sumario:Long-haul COVID-19, also called post-acute sequelae of SARS-CoV-2 (PASC), is a new illness caused by SARS-CoV-2 infection and characterized by the persistence of symptoms. The purpose of this cross-sectional study was to identify a distinct and significant temporal pattern of PASC symptoms (symptom type and onset) among a nationwide sample of PASC survivors (n = 5652). The sample was randomly sorted into two independent samples for exploratory (EFA) and confirmatory factor analyses (CFA). Five factors emerged from the EFA: (1) cold and flu-like symptoms, (2) change in smell and/or taste, (3) dyspnea and chest pain, (4) cognitive and visual problems, and (5) cardiac symptoms. The CFA had excellent model fit (x(2) = 513.721, df = 207, p < 0.01, TLI = 0.952, CFI = 0.964, RMSEA = 0.024). These findings demonstrate a novel symptom pattern for PASC. These findings can enable nurses in the identification of at-risk patients and facilitate early, systematic symptom management strategies for PASC.