Accumulation of mutations in antibody and CD8 T cell epitopes in a B cell depleted lymphoma patient with chronic SARS-CoV-2 infection

Antibodies against the spike protein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) can drive adaptive evolution in immunocompromised patients with chronic infection. Here we longitudinally analyze SARS-CoV-2 sequences in a B cell-depleted, lymphoma patient with chronic, ultimately...

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Detalles Bibliográficos
Autores principales: Khatamzas, Elham, Antwerpen, Markus H., Rehn, Alexandra, Graf, Alexander, Hellmuth, Johannes Christian, Hollaus, Alexandra, Mohr, Anne-Wiebe, Gaitzsch, Erik, Weiglein, Tobias, Georgi, Enrico, Scherer, Clemens, Stecher, Stephanie-Susanne, Gruetzner, Stefanie, Blum, Helmut, Krebs, Stefan, Reischer, Anna, Leutbecher, Alexandra, Subklewe, Marion, Dick, Andrea, Zange, Sabine, Girl, Philipp, Müller, Katharina, Weigert, Oliver, Hopfner, Karl-Peter, Stemmler, Hans-Joachim, von Bergwelt-Baildon, Michael, Keppler, Oliver T., Wölfel, Roman, Muenchhoff, Maximilian, Moosmann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508331/
https://www.ncbi.nlm.nih.gov/pubmed/36151076
http://dx.doi.org/10.1038/s41467-022-32772-5

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