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Serum dihydroceramides correlate with insulin sensitivity in humans and decrease insulin sensitivity in vitro

Serum ceramides, especially C16:0 and C18:0 species, are linked to CVD risk and insulin resistance, but details of this association are not well understood. We performed this study to quantify a broad range of serum sphingolipids in individuals spanning the physiologic range of insulin sensitivity a...

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Detalles Bibliográficos
Autores principales: Zarini, Simona, Brozinick, Joseph T., Zemski Berry, Karin A., Garfield, Amanda, Perreault, Leigh, Kerege, Anna, Bui, Hai Hoang, Sanders, Phil, Siddall, Parker, Kuo, Ming Shang, Bergman, Bryan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508341/
https://www.ncbi.nlm.nih.gov/pubmed/36030929
http://dx.doi.org/10.1016/j.jlr.2022.100270