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Serum dihydroceramides correlate with insulin sensitivity in humans and decrease insulin sensitivity in vitro
Serum ceramides, especially C16:0 and C18:0 species, are linked to CVD risk and insulin resistance, but details of this association are not well understood. We performed this study to quantify a broad range of serum sphingolipids in individuals spanning the physiologic range of insulin sensitivity a...
Autores principales: | Zarini, Simona, Brozinick, Joseph T., Zemski Berry, Karin A., Garfield, Amanda, Perreault, Leigh, Kerege, Anna, Bui, Hai Hoang, Sanders, Phil, Siddall, Parker, Kuo, Ming Shang, Bergman, Bryan C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508341/ https://www.ncbi.nlm.nih.gov/pubmed/36030929 http://dx.doi.org/10.1016/j.jlr.2022.100270 |
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