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Incisionless targeted adeno-associated viral vector delivery to the brain by focused ultrasound-mediated intranasal administration

BACKGROUND: Adeno-associated viral (AAV) vectors are currently the leading platform for gene therapy with the potential to treat a variety of central nervous system (CNS) diseases. There are numerous methods for delivering AAVs to the CNS, such as direct intracranial injection (DI), intranasal deliv...

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Detalles Bibliográficos
Autores principales:	Ye, Dezhuang, Yuan, Jinyun, Yang, Yaoheng, Yue, Yimei, Hu, Zhongtao, Fadera, Siaka, Chen, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508404/ https://www.ncbi.nlm.nih.gov/pubmed/36152518 http://dx.doi.org/10.1016/j.ebiom.2022.104277

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