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Macrophage Infiltration Initiates RIP3/MLKL-Dependent Necroptosis in Paclitaxel-Induced Neuropathic Pain

Paclitaxel (PTX) is a commonly used antitumor drug. Approximately 80% of all patients receiving PTX chemotherapy develop chemotherapy-induced peripheral neuropathy (CIPN), limiting the use of PTX. Moreover, CIPN responds poorly to conventional analgesics. Experimental evidence suggests that the neur...

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Detalles Bibliográficos
Autores principales:	Ma, Dongyang, Wang, Xiuli, Liu, Xin, Li, Zhao, Liu, Jiaxin, Cao, Jing, Wang, Guiying, Guo, Yuexian, Zhao, Shuang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508459/ https://www.ncbi.nlm.nih.gov/pubmed/36164389 http://dx.doi.org/10.1155/2022/1567210

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