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Transwell migration assay to interrogate human CAR-T cell chemotaxis

A major impediment to effective cellular therapies in solid tumors is the limited access of therapeutic cells to the tumor site. One strategy to overcome this challenge is to endow T cells with chemotactic properties required to access tumor tissue. Here, we present a chimeric antigen receptor (CAR)...

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Detalles Bibliográficos
Autores principales: Oner, Arman, Kobold, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508471/
https://www.ncbi.nlm.nih.gov/pubmed/36136753
http://dx.doi.org/10.1016/j.xpro.2022.101708