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Evaluation of Platelet Function Using Thromboelastography for a Patient With Pseudothrombocytopenia Requiring Cardiac Reoperation

Pseudothrombocytopenia (PTCP) is a phenomenon in which platelet aggregation occurs in vitro when an anticoagulant such as ethylenediaminetetraacetic acid (EDTA) is used in a blood sample, causing automated cell counters (ACC) to calculate a lower platelet count than the actual count. While a periphe...

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Autores principales: Kometani, Satoshi, Kawai, Michihiko, Teraoka, Nami, Miyazaki, Reo, Ikezaki, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508524/
https://www.ncbi.nlm.nih.gov/pubmed/36171853
http://dx.doi.org/10.7759/cureus.28366
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author Kometani, Satoshi
Kawai, Michihiko
Teraoka, Nami
Miyazaki, Reo
Ikezaki, Hiroyuki
author_facet Kometani, Satoshi
Kawai, Michihiko
Teraoka, Nami
Miyazaki, Reo
Ikezaki, Hiroyuki
author_sort Kometani, Satoshi
collection PubMed
description Pseudothrombocytopenia (PTCP) is a phenomenon in which platelet aggregation occurs in vitro when an anticoagulant such as ethylenediaminetetraacetic acid (EDTA) is used in a blood sample, causing automated cell counters (ACC) to calculate a lower platelet count than the actual count. While a peripheral blood smear is required to assess platelet count in PTCP accurately, such a time-consuming test is not accessible during the perioperative period. In this study, we evaluated platelet function using thromboelastography (TEG) for a patient with PTCP requiring cardiac reoperation. The preoperative TEG value of the patient was within the normal range, suggesting that TEG for PTCP reflects platelet function more accurately than ACC. Since there is an insufficient number of case reports on the use of TEG for PTCP, it is necessary to consider its usefulness not only during the perioperative period but also for other critical care.
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spelling pubmed-95085242022-09-27 Evaluation of Platelet Function Using Thromboelastography for a Patient With Pseudothrombocytopenia Requiring Cardiac Reoperation Kometani, Satoshi Kawai, Michihiko Teraoka, Nami Miyazaki, Reo Ikezaki, Hiroyuki Cureus Anesthesiology Pseudothrombocytopenia (PTCP) is a phenomenon in which platelet aggregation occurs in vitro when an anticoagulant such as ethylenediaminetetraacetic acid (EDTA) is used in a blood sample, causing automated cell counters (ACC) to calculate a lower platelet count than the actual count. While a peripheral blood smear is required to assess platelet count in PTCP accurately, such a time-consuming test is not accessible during the perioperative period. In this study, we evaluated platelet function using thromboelastography (TEG) for a patient with PTCP requiring cardiac reoperation. The preoperative TEG value of the patient was within the normal range, suggesting that TEG for PTCP reflects platelet function more accurately than ACC. Since there is an insufficient number of case reports on the use of TEG for PTCP, it is necessary to consider its usefulness not only during the perioperative period but also for other critical care. Cureus 2022-08-24 /pmc/articles/PMC9508524/ /pubmed/36171853 http://dx.doi.org/10.7759/cureus.28366 Text en Copyright © 2022, Kometani et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Anesthesiology
Kometani, Satoshi
Kawai, Michihiko
Teraoka, Nami
Miyazaki, Reo
Ikezaki, Hiroyuki
Evaluation of Platelet Function Using Thromboelastography for a Patient With Pseudothrombocytopenia Requiring Cardiac Reoperation
title Evaluation of Platelet Function Using Thromboelastography for a Patient With Pseudothrombocytopenia Requiring Cardiac Reoperation
title_full Evaluation of Platelet Function Using Thromboelastography for a Patient With Pseudothrombocytopenia Requiring Cardiac Reoperation
title_fullStr Evaluation of Platelet Function Using Thromboelastography for a Patient With Pseudothrombocytopenia Requiring Cardiac Reoperation
title_full_unstemmed Evaluation of Platelet Function Using Thromboelastography for a Patient With Pseudothrombocytopenia Requiring Cardiac Reoperation
title_short Evaluation of Platelet Function Using Thromboelastography for a Patient With Pseudothrombocytopenia Requiring Cardiac Reoperation
title_sort evaluation of platelet function using thromboelastography for a patient with pseudothrombocytopenia requiring cardiac reoperation
topic Anesthesiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508524/
https://www.ncbi.nlm.nih.gov/pubmed/36171853
http://dx.doi.org/10.7759/cureus.28366
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