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Tied up in knots: Untangling substrate recognition by the SPOUT methyltransferases

The SpoU-TrmD (SPOUT) methyltransferase superfamily was designated when structural similarity was identified between the transfer RNA–modifying enzymes TrmH (SpoU) and TrmD. SPOUT methyltransferases are found in all domains of life and predominantly modify transfer RNA or ribosomal RNA substrates, t...

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Detalles Bibliográficos
Autores principales: Strassler, Sarah E., Bowles, Isobel E., Dey, Debayan, Jackman, Jane E., Conn, Graeme L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508554/
https://www.ncbi.nlm.nih.gov/pubmed/35988649
http://dx.doi.org/10.1016/j.jbc.2022.102393