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Isoform a4 of the vacuolar ATPase a subunit promotes 4T1-12B breast cancer cell–dependent tumor growth and metastasis in vivo

The vacuolar H(+)-ATPase (V-ATPase) is an ATP-dependent proton pump that governs the pH of various intracellular compartments and also functions at the plasma membrane in certain cell types, including cancer cells. Membrane targeting of the V-ATPase is controlled by isoforms of subunit a, and we hav...

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Detalles Bibliográficos
Autores principales:	Su, Kevin, Collins, Michael P., McGuire, Christina M., Alshagawi, Mohammed A., Alamoudi, Mariam K., Li, Zhen, Forgac, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508560/ https://www.ncbi.nlm.nih.gov/pubmed/35988642 http://dx.doi.org/10.1016/j.jbc.2022.102395

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