YAP Activates STAT3 Signalling to Promote Colonic Epithelial Cell Proliferation in DSS-Induced Colitis and Colitis Associated Cancer

BACKGROUND AND AIMS: Yes-associated protein (YAP) is a key transcriptional coactivator of cell proliferation and differentiation. In this study, we sought to identify the roles of YAP in colonic epithelial regeneration and tumourigenesis. METHODS: Murine DSS-induced colitis and YAP overexpression mo...

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Detalles Bibliográficos
Autores principales: Deng, Feihong, Wu, Zengrong, Xu, Mengmeng, Xia, Pianpian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508680/
https://www.ncbi.nlm.nih.gov/pubmed/36164660
http://dx.doi.org/10.2147/JIR.S377077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508680/
https://www.ncbi.nlm.nih.gov/pubmed/36164660
http://dx.doi.org/10.2147/JIR.S377077

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