Design and lyophilization of lipid nanoparticles for mRNA vaccine and its robust immune response in mice and nonhuman primates

mRNA and lipid nanoparticles have emerged as powerful systems for the preparation of vaccines against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. The emergence of novel variants or the necessity of cold chain logistics for approved mRNA vaccines undermines the investigati...

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Detalles Bibliográficos
Autores principales: Suzuki, Yuta, Miyazaki, Takayuki, Muto, Hiroki, Kubara, Kenji, Mukai, Yohei, Watari, Ryuji, Sato, Shinya, Kondo, Keita, Tsukumo, Shin-ichi, Yasutomo, Koji, Ito, Masashi, Tsukahara, Kappei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508692/
https://www.ncbi.nlm.nih.gov/pubmed/36187052
http://dx.doi.org/10.1016/j.omtn.2022.09.017

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