Cargando…

A recurrent somatic missense mutation in GNAS gene identified in familial thyroid follicular cell carcinomas in German longhaired pointer dogs

BACKGROUND: We previously reported a familial thyroid follicular cell carcinoma (FCC) in a large number of Dutch German longhaired pointers and identified two deleterious germline mutations in the TPO gene associated with disease predisposition. However, the somatic mutation profile of the FCC in do...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Yun, Manders, Freek, Grinwis, Guy C. M., Groenen, Martien A. M., Crooijmans, Richard P. M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508735/
https://www.ncbi.nlm.nih.gov/pubmed/36151521
http://dx.doi.org/10.1186/s12864-022-08885-y