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A recurrent somatic missense mutation in GNAS gene identified in familial thyroid follicular cell carcinomas in German longhaired pointer dogs
BACKGROUND: We previously reported a familial thyroid follicular cell carcinoma (FCC) in a large number of Dutch German longhaired pointers and identified two deleterious germline mutations in the TPO gene associated with disease predisposition. However, the somatic mutation profile of the FCC in do...
Autores principales: | Yu, Yun, Manders, Freek, Grinwis, Guy C. M., Groenen, Martien A. M., Crooijmans, Richard P. M. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508735/ https://www.ncbi.nlm.nih.gov/pubmed/36151521 http://dx.doi.org/10.1186/s12864-022-08885-y |
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