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Higher levels of myelin are associated with higher resistance against tau pathology in Alzheimer’s disease

BACKGROUND: In Alzheimer’s disease (AD), fibrillar tau initially occurs locally and progresses preferentially between closely connected regions. However, the underlying sources of regional vulnerability to tau pathology remain unclear. Previous brain-autopsy findings suggest that the myelin levels—w...

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Detalles Bibliográficos
Autores principales: Rubinski, Anna, Franzmeier, Nicolai, Dewenter, Anna, Luan, Ying, Smith, Ruben, Strandberg, Olof, Ossenkoppele, Rik, Dichgans, Martin, Hansson, Oskar, Ewers, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508747/
https://www.ncbi.nlm.nih.gov/pubmed/36153607
http://dx.doi.org/10.1186/s13195-022-01074-9