Crosstalk between tumor-associated macrophages and tumor cells promotes chemoresistance via CXCL5/PI3K/AKT/mTOR pathway in gastric cancer

BACKGROUND: 5-fluorouracil (5-FU)-based chemotherapy regimen has been widely used for the treatment of gastric cancer, but meanwhile the development of chemotherapeutic resistance remains a major clinical challenge. Tumor microenvironment (TME) frequently correlates with the development of chemoresi...

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Detalles Bibliográficos
Autores principales: Su, Pengfei, Jiang, Lin, Zhang, Yingjing, Yu, Tian, Kang, Weiming, Liu, Yuqin, Yu, Jianchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508748/
https://www.ncbi.nlm.nih.gov/pubmed/36151545
http://dx.doi.org/10.1186/s12935-022-02717-5

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