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Comparative analysis of transcriptome remodeling in plaque-associated and plaque-distant microglia during amyloid-β pathology progression in mice

BACKGROUND: Research in recent years firmly established that microglial cells play an important role in the pathogenesis of Alzheimer's disease (AD). In parallel, a series of studies showed that, under both homeostatic and pathological conditions, microglia are a heterogeneous cell population....

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Detalles Bibliográficos
Autores principales: Hemonnot-Girard, Anne-Laure, Meersseman, Cédric, Pastore, Manuela, Garcia, Valentin, Linck, Nathalie, Rey, Catherine, Chebbi, Amine, Jeanneteau, Freddy, Ginsberg, Stephen D., Lachuer, Joël, Reynes, Christelle, Rassendren, François, Hirbec, Hélène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508749/
https://www.ncbi.nlm.nih.gov/pubmed/36153535
http://dx.doi.org/10.1186/s12974-022-02581-0