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Four Years of Disease-Free Survival After Conservative Treatment of Subglottic Adenoid Cystic Carcinoma
Adenoid cystic carcinoma (ACC) is a rare malignancy of the larynx. Surgical excision seems to be the preferred treatment modality; however, a paucity of high-evidence suggestions due to the small number of cases have been noted. Here we present the case of a 35-year-old woman with subglottic ACC who...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508788/ https://www.ncbi.nlm.nih.gov/pubmed/36171834 http://dx.doi.org/10.7759/cureus.28377 |
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author | Vardaxi, Chrysoula Skalias, Antonios Karamitsou, Paraskevi Forozidou, Evropi Poutoglidis, Alexandros |
author_facet | Vardaxi, Chrysoula Skalias, Antonios Karamitsou, Paraskevi Forozidou, Evropi Poutoglidis, Alexandros |
author_sort | Vardaxi, Chrysoula |
collection | PubMed |
description | Adenoid cystic carcinoma (ACC) is a rare malignancy of the larynx. Surgical excision seems to be the preferred treatment modality; however, a paucity of high-evidence suggestions due to the small number of cases have been noted. Here we present the case of a 35-year-old woman with subglottic ACC who denied laryngectomy and opted for concurrent chemotherapy and radiotherapy. She remains disease-free four years later. This case illustrates that concurrent chemoradiation, instead of laryngectomy, should be considered in selected cases. |
format | Online Article Text |
id | pubmed-9508788 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-95087882022-09-27 Four Years of Disease-Free Survival After Conservative Treatment of Subglottic Adenoid Cystic Carcinoma Vardaxi, Chrysoula Skalias, Antonios Karamitsou, Paraskevi Forozidou, Evropi Poutoglidis, Alexandros Cureus Otolaryngology Adenoid cystic carcinoma (ACC) is a rare malignancy of the larynx. Surgical excision seems to be the preferred treatment modality; however, a paucity of high-evidence suggestions due to the small number of cases have been noted. Here we present the case of a 35-year-old woman with subglottic ACC who denied laryngectomy and opted for concurrent chemotherapy and radiotherapy. She remains disease-free four years later. This case illustrates that concurrent chemoradiation, instead of laryngectomy, should be considered in selected cases. Cureus 2022-08-25 /pmc/articles/PMC9508788/ /pubmed/36171834 http://dx.doi.org/10.7759/cureus.28377 Text en Copyright © 2022, Vardaxi et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Otolaryngology Vardaxi, Chrysoula Skalias, Antonios Karamitsou, Paraskevi Forozidou, Evropi Poutoglidis, Alexandros Four Years of Disease-Free Survival After Conservative Treatment of Subglottic Adenoid Cystic Carcinoma |
title | Four Years of Disease-Free Survival After Conservative Treatment of Subglottic Adenoid Cystic Carcinoma |
title_full | Four Years of Disease-Free Survival After Conservative Treatment of Subglottic Adenoid Cystic Carcinoma |
title_fullStr | Four Years of Disease-Free Survival After Conservative Treatment of Subglottic Adenoid Cystic Carcinoma |
title_full_unstemmed | Four Years of Disease-Free Survival After Conservative Treatment of Subglottic Adenoid Cystic Carcinoma |
title_short | Four Years of Disease-Free Survival After Conservative Treatment of Subglottic Adenoid Cystic Carcinoma |
title_sort | four years of disease-free survival after conservative treatment of subglottic adenoid cystic carcinoma |
topic | Otolaryngology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508788/ https://www.ncbi.nlm.nih.gov/pubmed/36171834 http://dx.doi.org/10.7759/cureus.28377 |
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