The absence of the queuosine tRNA modification leads to pleiotropic phenotypes revealing perturbations of metal and oxidative stress homeostasis in Escherichia coli K12

Queuosine (Q) is a conserved hypermodification of the wobble base of tRNA containing GUN anticodons but the physiological consequences of Q deficiency are poorly understood in bacteria. This work combines transcriptomic, proteomic and physiological studies to characterize a Q-deficient Escherichia c...

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Detalles Bibliográficos
Autores principales: Pollo-Oliveira, Leticia, Davis, Nick K, Hossain, Intekhab, Ho, Peiying, Yuan, Yifeng, Salguero García, Pedro, Pereira, Cécile, Byrne, Shane R, Leng, Jiapeng, Sze, Melody, Blaby-Haas, Crysten E, Sekowska, Agnieszka, Montoya, Alvaro, Begley, Thomas, Danchin, Antoine, Aalberts, Daniel P, Angerhofer, Alexander, Hunt, John, Conesa, Ana, Dedon, Peter C, de Crécy-Lagard, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508795/
https://www.ncbi.nlm.nih.gov/pubmed/36066904
http://dx.doi.org/10.1093/mtomcs/mfac065

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