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The consequences of differential origin licensing dynamics in distinct chromatin environments

Eukaryotic chromosomes contain regions of varying accessibility, yet DNA replication factors must access all regions. The first replication step is loading MCM complexes to license replication origins during the G1 cell cycle phase. It is not yet known how mammalian MCM complexes are adequately dist...

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Detalles Bibliográficos
Autores principales:	Mei, Liu, Kedziora, Katarzyna M, Song, Eun-Ah, Purvis, Jeremy E, Cook, Jeanette Gowen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	NAR Breakthrough Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508807/ https://www.ncbi.nlm.nih.gov/pubmed/35079814 http://dx.doi.org/10.1093/nar/gkac003

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