Changes in the architecture and abundance of replication intermediates delineate the chronology of DNA damage tolerance pathways at UV-stalled replication forks in human cells

DNA lesions in S phase threaten genome stability. The DNA damage tolerance (DDT) pathways overcome these obstacles and allow completion of DNA synthesis by the use of specialised translesion (TLS) DNA polymerases or through recombination-related processes. However, how these mechanisms coordinate wi...

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Detalles Bibliográficos
Autores principales: Benureau, Yann, Pouvelle, Caroline, Dupaigne, Pauline, Baconnais, Sonia, Moreira Tavares, Eliana, Mazón, Gerard, Despras, Emmanuelle, Le Cam, Eric, Kannouche, Patricia L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508826/
https://www.ncbi.nlm.nih.gov/pubmed/36107774
http://dx.doi.org/10.1093/nar/gkac746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508826/
https://www.ncbi.nlm.nih.gov/pubmed/36107774
http://dx.doi.org/10.1093/nar/gkac746

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