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Mitochondrial stress induces AREG expression and epigenomic remodeling through c-JUN and YAP-mediated enhancer activation

Nucleus–mitochondria crosstalk is essential for cellular and organismal homeostasis. Although anterograde (nucleus-to-mitochondria) pathways have been well characterized, retrograde (mitochondria-to-nucleus) pathways remain to be clarified. Here, we found that mitochondrial dysfunction triggered a r...

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Detalles Bibliográficos
Autores principales:	Hino, Yuko, Nagaoka, Katsuya, Oki, Shinya, Etoh, Kan, Hino, Shinjiro, Nakao, Mitsuyoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508833/ https://www.ncbi.nlm.nih.gov/pubmed/36095121 http://dx.doi.org/10.1093/nar/gkac735

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