Retrospective Cohort Study of the Incidence and Outcomes of Jarisch-Herxheimer Reactions After Treatment of Infectious Syphilis in Late Pregnancy

Of 39 pregnant women at ≥20 weeks' gestation treated with benzathine penicillin G for infectious syphilis, we identified only 2 mild Jarisch-Herxheimer reactions. There were no immediate fetal sequelae. Data from our study do not support the recommendation for routine admission for the treatmen...

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Autores principales: Macumber, Stephen, Singh, Ameeta E., Gratrix, Jennifer, Robinson, Joan L., Smyczek, Petra, Rathjen, Lindsay, Sklar, Cameron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508967/
https://www.ncbi.nlm.nih.gov/pubmed/35093982
http://dx.doi.org/10.1097/OLQ.0000000000001610
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author Macumber, Stephen
Singh, Ameeta E.
Gratrix, Jennifer
Robinson, Joan L.
Smyczek, Petra
Rathjen, Lindsay
Sklar, Cameron
author_facet Macumber, Stephen
Singh, Ameeta E.
Gratrix, Jennifer
Robinson, Joan L.
Smyczek, Petra
Rathjen, Lindsay
Sklar, Cameron
author_sort Macumber, Stephen
collection PubMed
description Of 39 pregnant women at ≥20 weeks' gestation treated with benzathine penicillin G for infectious syphilis, we identified only 2 mild Jarisch-Herxheimer reactions. There were no immediate fetal sequelae. Data from our study do not support the recommendation for routine admission for the treatment of infectious syphilis in late pregnancy.
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spelling pubmed-95089672022-10-03 Retrospective Cohort Study of the Incidence and Outcomes of Jarisch-Herxheimer Reactions After Treatment of Infectious Syphilis in Late Pregnancy Macumber, Stephen Singh, Ameeta E. Gratrix, Jennifer Robinson, Joan L. Smyczek, Petra Rathjen, Lindsay Sklar, Cameron Sex Transm Dis Notes Of 39 pregnant women at ≥20 weeks' gestation treated with benzathine penicillin G for infectious syphilis, we identified only 2 mild Jarisch-Herxheimer reactions. There were no immediate fetal sequelae. Data from our study do not support the recommendation for routine admission for the treatment of infectious syphilis in late pregnancy. Lippincott Williams & Wilkins 2022-10 2022-01-29 /pmc/articles/PMC9508967/ /pubmed/35093982 http://dx.doi.org/10.1097/OLQ.0000000000001610 Text en Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Sexually Transmitted Diseases Association. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Notes
Macumber, Stephen
Singh, Ameeta E.
Gratrix, Jennifer
Robinson, Joan L.
Smyczek, Petra
Rathjen, Lindsay
Sklar, Cameron
Retrospective Cohort Study of the Incidence and Outcomes of Jarisch-Herxheimer Reactions After Treatment of Infectious Syphilis in Late Pregnancy
title Retrospective Cohort Study of the Incidence and Outcomes of Jarisch-Herxheimer Reactions After Treatment of Infectious Syphilis in Late Pregnancy
title_full Retrospective Cohort Study of the Incidence and Outcomes of Jarisch-Herxheimer Reactions After Treatment of Infectious Syphilis in Late Pregnancy
title_fullStr Retrospective Cohort Study of the Incidence and Outcomes of Jarisch-Herxheimer Reactions After Treatment of Infectious Syphilis in Late Pregnancy
title_full_unstemmed Retrospective Cohort Study of the Incidence and Outcomes of Jarisch-Herxheimer Reactions After Treatment of Infectious Syphilis in Late Pregnancy
title_short Retrospective Cohort Study of the Incidence and Outcomes of Jarisch-Herxheimer Reactions After Treatment of Infectious Syphilis in Late Pregnancy
title_sort retrospective cohort study of the incidence and outcomes of jarisch-herxheimer reactions after treatment of infectious syphilis in late pregnancy
topic Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508967/
https://www.ncbi.nlm.nih.gov/pubmed/35093982
http://dx.doi.org/10.1097/OLQ.0000000000001610
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