Cargando…

Relationship between MTHFR C677T, homocysteine, and ischemic stroke in a large sample of the Han Chinese population

Ischemic stroke, one of the prevalent causes of death and disability worldwide, is linked to environmental and genetic factors, including polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene involved in homocysteine metabolism. The present study aimed to explore the relationship bet...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jin, Ming, Wang, Ningning, Li, Xueyan, Zhang, Hao, Zhou, Jexin, Cong, Mingyu, Niu, Jun, Lin, Chongyang, Hu, Ying, Wu, Nan, Liu, Jicheng, Zhang, Keyong, Qiu, Changchun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509028/ https://www.ncbi.nlm.nih.gov/pubmed/36197177 http://dx.doi.org/10.1097/MD.0000000000030562

Ejemplares similares

A possible synergistic effect of MTHFR C677T polymorphism on homocysteine level variations increased risk for ischemic stroke
por: Li, Aifan, et al.
Publicado: (2017)

Homocysteine and the C677T Gene Polymorphism of Its Key Metabolic Enzyme MTHFR Are Risk Factors of Early Renal Damage in Hypertension in a Chinese Han Population
por: Yun, Lin, et al.
Publicado: (2015)

Influence of food groups on plasma total homocysteine for specific MTHFR C677T genotypes in Chinese population
por: Zeng, Qiang, et al.
Publicado: (2016)

Homocysteine levels, H-Hypertension, and the MTHFR C677T genotypes: A complex interaction
por: Al Hageh, Cynthia, et al.
Publicado: (2023)

A novel haplotype of low-frequency variants in the aldosterone synthase gene among northern Han Chinese with essential hypertension
por: Zhang, Hao, et al.
Publicado: (2017)

The MTHFR C677T Polymorphism and Risk of Intracerebral Hemorrhage in a Chinese Han Population
por: Hu, Xin, et al.
Publicado: (2016)

The effect of the MTHFR C677T mutation on athletic performance and the homocysteine level of soccer players and sedentary individuals
por: Dinç, Nurten, et al.
Publicado: (2016)

Role of homocysteine & MTHFR C677T gene polymorphism as risk factors for coronary artery disease in young Indians
por: Gupta, Santosh Kumar, et al.
Publicado: (2012)

Meta-analyses of Blood Homocysteine Levels for Gender and Genetic Association Studies of the MTHFR C677T Polymorphism in Schizophrenia
por: Nishi, Akira, et al.
Publicado: (2014)

Association of Homocysteine, Methionine, and MTHFR 677C>T Polymorphism With Rate of Cardiovascular Multimorbidity Development in Older Adults in Sweden
por: Calderón-Larrañaga, Amaia, et al.
Publicado: (2020)

Meta-analysis study to evaluate the association of MTHFR C677T polymorphism with risk of ischemic stroke
por: Abhinand, P.A., et al.
Publicado: (2017)

A plasma proteomics method reveals links between ischemic stroke and MTHFR C677T genotype
por: Zhang, Zhenchang, et al.
Publicado: (2017)

Influence of Combined Methionine Synthase (MTR 2756A > G) and Methylenetetrahydrofolate Reductase (MTHFR 677C > T) Polymorphisms to Plasma Homocysteine Levels in Korean Patients with Ischemic Stroke
por: Kim, Ok Joon, et al.
Publicado: (2007)

Association Study of MTHFR C677T Polymorphism and Birth Body Mass With Risk of Autism in Chinese Han Population
por: Zhang, Jishui, et al.
Publicado: (2021)

A prospective cohort study of MTHFR C677T gene polymorphism and its influence on the therapeutic effect of homocysteine in stroke patients with hyperhomocysteinemia
por: Du, Xiaoxia, et al.
Publicado: (2020)

Homocysteine, MTHFR C677T gene polymorphism, folic acid and vitamin B 12 in patients with retinal vein occlusion
por: Ferrazzi, Paola, et al.
Publicado: (2005)

Association of MTHFR C677T Genotype With Ischemic Stroke Is Confined to Cerebral Small Vessel Disease Subtype
por: Rutten-Jacobs, Loes C.A., et al.
Publicado: (2016)

Association Between MTHFR C677T Polymorphism and Susceptibility to Autism Spectrum Disorders: A Meta-Analysis in Chinese Han Population
por: Li, Chen-Xi, et al.
Publicado: (2021)

MTHFR c.677C>T Inhibits Cell Proliferation and Decreases Prostate Cancer Susceptibility in the Han Chinese Population in Shanghai
por: Wu, Jun-Long, et al.
Publicado: (2016)

CACNA1C rs1006737 SNP increases the risk of essential hypertension in both Chinese Han and ethnic Russian people of Northeast Asia
por: Zhang, Hao, et al.
Publicado: (2021)

Association between serum 5-methyltetrahydrofolate and homocysteine in Chinese hypertensive participants with different MTHFR C677T polymorphisms: a cross-sectional study
por: Cheng, Yu, et al.
Publicado: (2022)

Relationship of MTHFR Gene 677C→T Polymorphism, Homocysteine, and Estimated Glomerular Filtration Rate Levels With the Risk of New-Onset Diabetes
por: Qin, Xianhui, et al.
Publicado: (2015)

Mendelian Randomization Analysis of the Effect of Maternal Homocysteine During Pregnancy, as Represented by Maternal MTHFR C677T Genotype, on Birth Weight
por: Lee, Hye Ah, et al.
Publicado: (2013)

Polymorphisms C677T and A1298C of MTHFR Gene: Homocysteine Levels and Prothrombotic Biomarkers in Coronary and Pulmonary Thromboembolic Disease
por: Lupi-Herrera, Eulo, et al.
Publicado: (2018)

Regional distribution of the MTHFR C677T polymorphism in Chinese females
por: Lin, Hua, et al.
Publicado: (2023)

Relationship of Methylenetetrahydrofolate Reductase (MTHFR) C677T Variation With Susceptibility of Patients With Ischemic Stroke: A Meta-Analysis
por: Kumar, Pramod, et al.
Publicado: (2022)

Homocysteine and all-cause mortality in hypertensive adults without pre-existing cardiovascular conditions: Effect modification by MTHFR C677T polymorphism
por: Xu, Benjamin, et al.
Publicado: (2017)

Human genetic selection on the MTHFR 677C>T polymorphism
por: Mayor-Olea, Álvaro, et al.
Publicado: (2008)

Analysis of the MTHFR C677T variant with migraine phenotypes
por: Liu, Annie, et al.
Publicado: (2010)

The C677T Polymorphism in MTHFR Is Not Associated with Migraine in Portugal
por: Ferro, Anabela, et al.
Publicado: (2008)

Haplotype-based association of renin gene polymorphisms with essential hypertension in Han population of northern china
por: Zhang, Guoping, et al.
Publicado: (2017)

MTHFR C677T and MTR A2756G polymorphisms and the homocysteine lowering efficacy of different doses of folic acid in hypertensive Chinese adults
por: Qin, Xianhui, et al.
Publicado: (2012)

MTHFR gene C677T and A1298C polymorphisms and homocysteine levels in primary open angle and primary closed angle glaucoma
por: Micheal, Shazia, et al.
Publicado: (2009)

Association of homocysteine and methylene tetrahydrofolate reductase (MTHFR C677T) gene polymorphism with coronary artery disease (CAD) in the population of North India
por: Tripathi, Rajneesh, et al.
Publicado: (2010)

The Different Relationship between Homocysteine and Uric Acid Levels with Respect to the MTHFR C677T Polymorphism According to Gender in Patients with Cognitive Impairment
por: Kim, Hee-Jin, et al.
Publicado: (2020)

Association of angiotensin-converting enzyme 2 gene polymorphism and enzymatic activity with essential hypertension in different gender: A case–control study
por: Zhang, Qi, et al.
Publicado: (2018)

Association of the methylenetetrahydrofolate reductase (MTHFR) gene variant C677T with serum homocysteine levels and the severity of ischaemic stroke: a case–control study in the southwest of China
por: Huang, Lu-Wen, et al.
Publicado: (2022)

Homocysteine Metabolism Gene Polymorphisms (MTHFR C677T, MTHFR A1298C, MTR A2756G and MTRR A66G) Jointly Elevate the Risk of Folate Deficiency
por: Li, Wen-Xing, et al.
Publicado: (2015)

MTHFR C677T gene polymorphism and the severity of coronary lesions in acute coronary syndrome
por: Li, Miao-Nan, et al.
Publicado: (2017)

MTHFR Gene C677T Polymorphism in Autism Spectrum Disorders
por: Sener, Elif Funda, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_o70gmohuqle3euf2gd09ct6b5o