Roles of activator protein-2 gamma in breast cancer: A narrative review (SANRA)

Activator protein-2 gamma (AP-2γ) is a crucial transcription factor involved in breast cancer development. Abnormal expression and activity of AP-2γ have also been identified as important markers of malignancy. In the last decade, the importance of AP-2γ in breast cancer progression has been widely...

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Autores principales: Zhang, Yifei, Mostafa, Asal AA, Sriboonvorakul, Natthida, Hu, Jiamiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509159/
https://www.ncbi.nlm.nih.gov/pubmed/36197225
http://dx.doi.org/10.1097/MD.0000000000030587
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author Zhang, Yifei
Mostafa, Asal AA
Sriboonvorakul, Natthida
Hu, Jiamiao
author_facet Zhang, Yifei
Mostafa, Asal AA
Sriboonvorakul, Natthida
Hu, Jiamiao
author_sort Zhang, Yifei
collection PubMed
description Activator protein-2 gamma (AP-2γ) is a crucial transcription factor involved in breast cancer development. Abnormal expression and activity of AP-2γ have also been identified as important markers of malignancy. In the last decade, the importance of AP-2γ in breast cancer progression has been widely studied. In this review, we summarize the current knowledge on the regulatory roles of AP-2γ in breast cancer oncogenesis and progression and its potential as a diagnostic biomarker and drug target in breast cancer treatment.
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spelling pubmed-95091592022-09-26 Roles of activator protein-2 gamma in breast cancer: A narrative review (SANRA) Zhang, Yifei Mostafa, Asal AA Sriboonvorakul, Natthida Hu, Jiamiao Medicine (Baltimore) Research Article Activator protein-2 gamma (AP-2γ) is a crucial transcription factor involved in breast cancer development. Abnormal expression and activity of AP-2γ have also been identified as important markers of malignancy. In the last decade, the importance of AP-2γ in breast cancer progression has been widely studied. In this review, we summarize the current knowledge on the regulatory roles of AP-2γ in breast cancer oncogenesis and progression and its potential as a diagnostic biomarker and drug target in breast cancer treatment. Lippincott Williams & Wilkins 2022-09-23 /pmc/articles/PMC9509159/ /pubmed/36197225 http://dx.doi.org/10.1097/MD.0000000000030587 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Zhang, Yifei
Mostafa, Asal AA
Sriboonvorakul, Natthida
Hu, Jiamiao
Roles of activator protein-2 gamma in breast cancer: A narrative review (SANRA)
title Roles of activator protein-2 gamma in breast cancer: A narrative review (SANRA)
title_full Roles of activator protein-2 gamma in breast cancer: A narrative review (SANRA)
title_fullStr Roles of activator protein-2 gamma in breast cancer: A narrative review (SANRA)
title_full_unstemmed Roles of activator protein-2 gamma in breast cancer: A narrative review (SANRA)
title_short Roles of activator protein-2 gamma in breast cancer: A narrative review (SANRA)
title_sort roles of activator protein-2 gamma in breast cancer: a narrative review (sanra)
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509159/
https://www.ncbi.nlm.nih.gov/pubmed/36197225
http://dx.doi.org/10.1097/MD.0000000000030587
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AT hujiamiao rolesofactivatorprotein2gammainbreastcanceranarrativereviewsanra

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