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MKK4 Knockdown Plays a Protective Role in Hemorrhagic Shock-Induced Liver Injury through the JNK Pathway

Hemorrhagic shock (HS) triggers tissue hypoxia and organ failure during severe blood loss, and the liver is sensitive to HS. Mitogen-activated protein kinase kinase 4 (MKK4) activates the c-Jun NH2-terminal kinase (JNK) pathway, and its expression is upregulated in the serum of HS patients and mouse...

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Detalles Bibliográficos
Autores principales:	Yao, Hao, Gao, Yu, Han, Jiahui, Wang, Yan, Cai, Jimin, Rui, Yongjun, Ge, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509254/ https://www.ncbi.nlm.nih.gov/pubmed/36164393 http://dx.doi.org/10.1155/2022/5074153

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