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SARS-CoV-2-induced hypomethylation of the ferritin heavy chain (FTH1) gene underlies serum hyperferritinemia in severe COVID-19 patients

High serum ferritin (hyperferritinemia), a reliable hallmark of severe COVID-19 often associates with a moderate decrease in serum iron (hypoferremia) and a moderate increase in serum hepcidin. This suggests that hyperferritinemia in severe COVID-19 is reflective of inflammation rather than iron ove...

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Detalles Bibliográficos
Autores principales: Muhammad, Jibran Sualeh, ElGhazali, Gehad, Shafarin, Jasmin, Mohammad, Mohammad G., Abu-Qiyas, Ameera, Hamad, Mawieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509293/
https://www.ncbi.nlm.nih.gov/pubmed/36183555
http://dx.doi.org/10.1016/j.bbrc.2022.09.083