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Inflammatory gut as a pathologic and therapeutic target in Parkinson’s disease
Parkinson’s disease (PD) remains a significant unmet clinical need. Gut dysbiosis stands as a PD pathologic source and therapeutic target. Here, we assessed the role of the gut-brain axis in PD pathology and treatment. Adult transgenic (Tg) α-synuclein-overexpressing mice served as subjects and were...
Autores principales: | Lee, Jea-Young, Wang, Zhen-Jie, Moscatello, Alexa, Kingsbury, Chase, Cozene, Blaise, Farooq, Jeffrey, Saft, Madeline, Sadanandan, Nadia, Gonzales-Portillo, Bella, Zhang, Henry, Salazar, Felipe Esparza, Toledo, Alma Rosa Lezama, Monroy, Germán Rivera, Berlet, Reed, Sanberg, Cyndy D., Sanberg, Paul R., Borlongan, Cesario V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509357/ https://www.ncbi.nlm.nih.gov/pubmed/36153318 http://dx.doi.org/10.1038/s41420-022-01175-2 |
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