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Inflammatory gut as a pathologic and therapeutic target in Parkinson’s disease

Parkinson’s disease (PD) remains a significant unmet clinical need. Gut dysbiosis stands as a PD pathologic source and therapeutic target. Here, we assessed the role of the gut-brain axis in PD pathology and treatment. Adult transgenic (Tg) α-synuclein-overexpressing mice served as subjects and were...

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Detalles Bibliográficos
Autores principales: Lee, Jea-Young, Wang, Zhen-Jie, Moscatello, Alexa, Kingsbury, Chase, Cozene, Blaise, Farooq, Jeffrey, Saft, Madeline, Sadanandan, Nadia, Gonzales-Portillo, Bella, Zhang, Henry, Salazar, Felipe Esparza, Toledo, Alma Rosa Lezama, Monroy, Germán Rivera, Berlet, Reed, Sanberg, Cyndy D., Sanberg, Paul R., Borlongan, Cesario V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509357/
https://www.ncbi.nlm.nih.gov/pubmed/36153318
http://dx.doi.org/10.1038/s41420-022-01175-2

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