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Mannan-binding lectin serine protease-2 (MASP-2) in human kidney and its relevance for proteolytic activation of the epithelial sodium channel

Proteolytic activation of the renal epithelial sodium channel (ENaC) is increased by aldosterone. The aldosterone-sensitive protease remains unidentified. In humans, elevated circulating aldosterone is associated with increased urinary extracellular vesicle (uEVs) excretion of mannan-binding lectin...

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Detalles Bibliográficos
Autores principales:	Zachar, Rikke, Thiel, Steffen, Hansen, Søren, Henriksen, Maiken Lumby, Skjoedt, Mikkel-Ole, Skjodt, Karsten, Hamzaei, Zohra, Madsen, Kirsten, Lund, Lars, Hummler, Edith, Svenningsen, Per, Jensen, Boye Lagerbon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509361/ https://www.ncbi.nlm.nih.gov/pubmed/36153401 http://dx.doi.org/10.1038/s41598-022-20213-8

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