Recruitment of LEF1 by Pontin chromatin modifier amplifies TGFBR2 transcription and activates TGFβ/SMAD signalling during gliomagenesis

Synergies of transcription factors, chromatin modifiers and their target genes are vital for cell fate determination in human cancer. Although the importance of numerous epigenetic machinery for regulating gliomagenesis has been previously recognized, how chromatin modifiers collaborate with specifi...

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Detalles Bibliográficos
Autores principales: Zhou, Xuexia, Li, Xuebing, Wang, Run, Hua, Dan, Sun, Cuiyun, Yu, Lin, Shi, Cuijuan, Luo, Wenjun, Jiang, Zhendong, An, Wenzhe, Wang, Qian, Yu, Shizhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509381/
https://www.ncbi.nlm.nih.gov/pubmed/36153326
http://dx.doi.org/10.1038/s41419-022-05265-y

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